Jian Du Selected Research

N1- (4- (3- isopropyl- 2- methylindazol- 5- yl)pyrimidin- 2- yl)- N4- tetrahydropyran- 4- yl- cyclohexane- 1,4- diamine

6/2014

A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models.

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Jian Du Research Topics

Disease

35	Neoplasms (Cancer) 01/2022 - 12/2002
14	Hepatocellular Carcinoma (Hepatoma) 05/2017 - 01/2012
13	Inflammation (Inflammations) 01/2021 - 10/2013
6	Toxoplasmosis 02/2022 - 08/2013
6	Infections 02/2022 - 01/2015
6	Hypoxia (Hypoxemia) 01/2022 - 07/2014
6	Body Weight (Weight, Body) 01/2021 - 08/2009
6	Non-alcoholic Fatty Liver Disease 01/2021 - 10/2014
5	Reperfusion Injury 01/2022 - 01/2016
5	Ischemia 01/2022 - 06/2006
5	Neuroinflammatory Diseases 01/2021 - 01/2019
5	Parkinson Disease (Parkinson's Disease) 08/2020 - 11/2010
4	Carcinogenesis 01/2022 - 07/2007
4	Type 2 Diabetes Mellitus (MODY) 07/2021 - 01/2014
4	Pancreatic Neoplasms (Pancreatic Cancer) 06/2021 - 04/2012
4	Tuberculosis (Tuberculoses) 12/2020 - 12/2015
3	Osteoporosis 09/2022 - 09/2011
3	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 11/2021 - 01/2021
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 02/2021 - 06/2006
3	Pain (Aches) 01/2021 - 11/2015
3	Lung Neoplasms (Lung Cancer) 11/2013 - 12/2007
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 08/2009 - 08/2007
3	Genomic Instability 05/2008 - 12/2002
3	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 06/2007 - 09/2003
2	Latent Infection 02/2022 - 08/2014
2	Cysts 02/2022 - 01/2021
2	Breast Neoplasms (Breast Cancer) 01/2022 - 09/2017
2	Adenocarcinoma 01/2022 - 06/2021
2	Wounds and Injuries (Trauma) 12/2021 - 01/2021
2	Eosinophilic Esophagitis 12/2021 - 10/2019
2	Mental Disorders (Mental Disorder) 11/2021 - 06/2012
2	Hepatitis B 11/2021 - 01/2015
2	Meningococcal Meningitis 01/2021 - 01/2021
2	Chickenpox 01/2021 - 01/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 01/2020
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 11/2020
2	Peripheral Nerve Injuries 01/2021 - 02/2018
2	Carcinoma (Carcinomatosis) 11/2020 - 09/2017
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 02/2019

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 09/2022 - 10/2009
15	VaccinesIBA 11/2022 - 11/2010
11	Pharmaceutical PreparationsIBA 07/2021 - 12/2007
8	Glucose (Dextrose)FDA LinkGeneric 09/2022 - 06/2002
7	LipidsIBA 09/2022 - 07/2007
7	Biomarkers (Surrogate Marker)IBA 12/2021 - 09/2012
6	Biological ProductsIBA 09/2022 - 12/2007
6	LipopolysaccharidesIBA 01/2021 - 01/2019
6	Phosphotransferases (Kinase)IBA 12/2019 - 07/2007
5	EnzymesIBA 11/2022 - 01/2018
5	Long Noncoding RNAIBA 01/2022 - 01/2019
5	Jiedu Xiaozheng YinIBA 02/2017 - 01/2013
5	fuzheng yiliuIBA 08/2014 - 09/2011
4	AntibodiesIBA 11/2022 - 01/2019
4	Therapeutic UsesIBA 06/2021 - 12/2015
4	Oxygen (Dioxygen)IBA 02/2021 - 07/2014
4	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2019
4	Messenger RNA (mRNA)IBA 01/2020 - 03/2005
4	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020 - 10/2014
4	Insulin (Novolin)FDA Link 02/2019 - 03/2005
4	Interleukin-2 (IL2)IBA 05/2017 - 09/2011
4	DNA (Deoxyribonucleic Acid)IBA 02/2015 - 01/2003
4	Capsules (Microcapsules)IBA 02/2012 - 09/2003
3	ImmunosorbentsIBA 11/2022 - 01/2019
3	Immunoglobulin G (IgG)IBA 11/2022 - 01/2019
3	abemaciclibIBA 01/2022 - 09/2017
3	bedaquiline (R207910)IBA 11/2021 - 01/2021
3	CytokinesIBA 01/2021 - 11/2009
3	Liraglutide FDA Link 11/2020 - 05/2015
3	Peptides (Polypeptides)IBA 01/2020 - 01/2018
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/2017 - 08/2013
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2017 - 09/2011
3	Caspase 3 (Caspase-3)IBA 01/2017 - 06/2006
3	ethyl acetateIBA 08/2015 - 01/2013
3	Aurora KinasesIBA 05/2008 - 12/2002
3	KangxinIBA 06/2007 - 09/2003
2	Rubella VaccineIBA 11/2022 - 01/2017
2	ProteomeIBA 01/2022 - 01/2021
2	Transcription Factors (Transcription Factor)IBA 01/2022 - 11/2020
2	Hormones (Hormone)IBA 01/2022 - 09/2017
2	astragaloside AIBA 01/2022 - 01/2019
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 10/2013
2	HydrogelsIBA 12/2021 - 07/2019
2	Hepatitis B Vaccines (Hepatitis B Vaccine)IBA 11/2021 - 01/2017
2	gamma- hydroxy- gamma- ethyl- gamma- phenylbutyramide (HEPB)IBA 11/2021 - 01/2015
2	Sirolimus (Rapamycin)FDA Link 02/2021 - 11/2020
2	Competitive Endogenous RNAIBA 01/2021 - 11/2020
2	Untranslated RNA (Noncoding RNA)IBA 01/2021 - 11/2020
2	Amino Acids FDA Link 01/2021 - 07/2007
2	CateninsIBA 11/2020 - 12/2014
2	Tumor Biomarkers (Tumor Markers)IBA 11/2020 - 09/2012
2	Mechanistic Target of Rapamycin Complex 1IBA 11/2020 - 11/2018
2	TOR Serine-Threonine KinasesIBA 11/2020 - 11/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 03/2013
2	isovitexinIBA 01/2020 - 01/2019
2	farrerolIBA 01/2020 - 10/2019

Therapy/Procedure

22	Therapeutics 04/2022 - 04/2012
6	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2017 - 01/2013
5	Drug Therapy (Chemotherapy) 01/2017 - 12/2007
3	Liver Transplantation 01/2022 - 01/2021
2	Hepatectomy 01/2022 - 01/2021